Ellen Pompeo details private conversation with Grey's Anatomy co-star Eric Dane after revealing ALS diagnosis


The 53-year-old, who appeared on Grey's Anatomy from 2006 to 2012, announced in April he had been diagnosed with ALS, also known as Lou Gehrig's disease


Split image of Eric Dane and Ellen Pompeo© Getty Images
Beatriz Colon
Beatriz ColonNew York Writer - New York
February 5, 2026
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Eric Dane has had the support of both his loved ones and his former co-stars ever since announcing his battle with ALS.

The beloved Grey's Anatomy alum revealed he was diagnosed with the neurodegenerative disease also known as Lou Gehrig's disease earlier this year, but has continued working and making occasional public appearances when possible. 

Per the Mayo Clinic, amyotrophic lateral sclerosis, for which there is no cure, affects nerve cells in the brain and spinal cord, causing loss of muscle control, and gets worse over time. ALS life expectancy averages two to five years after diagnosis, but can vary greatly.

Zachary Quinto as Dr. Oliver Wolf, Eric Dane as Matthew Ramati, Madchen Amick as Alicia Ramati on Brilliant Minds season two© Getty Images
Eric recently guest starred as a firefighter diagnosed with ALS on Brilliant Minds

Among those to support Eric in the wake of his heartbreaking announcement was none other than Ellen Pompeo, who he worked with for several years on Grey's Anatomy, as Patrick Dempsey's best friend (and brief foe) Dr. Mark Sloan.

People reports that in late January, both Ellen and Eric appeared via pre-taped messages at the ALS Network Champions for Cures & Care Gala held at the Pasadena Convention Center. In her message, Ellen first recalled of Eric: "I remember when he came in as McSteamy and us having instant electric chemistry, and I immediately just fell in love with him."

"As soon as I heard about his diagnosis, I texted him, and I said, 'I'm here if you want to speak,'" she shared, and revealed that her "phone rang 30 seconds later."

SANDRA OH, ERIC DANE, ELLEN POMPEO on Grey's Anatomy season 8 in 2011© Getty Images
Ellen as Meredith Grey, Eric as Mark Sloan, and Sandra Oh as Christina Yang in 2011

Detailing the conversation, she further shared that she told Eric she would help him with "whatever you need, however I can help. I love you."

"I'm really proud of you," she added of Dane in her message, maintaining: "I love you so much and I am honored to get to speak about you today."

Patrick is also among some of Eric's former co-stars to share both public and private support. In January, he told Parade he and Eric have been keeping in touch via text to "see how he's doing," and called the McSteamy actor "courageous."

Eric Dane and actress Ellen Pompeo attend the party for Dane and Grey's Anatomy cast members hosted by Men's Heath magazine at Tenjune May 14, 2007 in New York City© Getty Images
The former co-stars in 2007

"I think he's been incredibly courageous in the face of this horrible disease. He's such a wonderful human being," he said, adding: "He has such a great sense of humor, and he's so intelligent. I've always enjoyed working and being around Eric."

His daughters are his main motivation to keep going© WireImage
Eric with his ex Rebecca and their daughters in 2017

He nonetheless noted that the situation is "heartbreaking," maintaining: "It really is. For him and for his family. You feel for them when you see this terrible disease and how quickly it attacks the body. But he's bringing a lot of light to that, and he's using his platform in a positive way. I wish him the best."

Eric shares daughters Billie, 15, and Georgia, 14, with wife Rebecca Gayheart, who he married in 2004. Though they separated in 2018, they never filed for divorce, and though they are not together, they have remained close, with Rebecca being part of his caregivers

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