The cast of E.R. will always have love for each other — and rejoice in a reunion.
Most recently, it was Julianna Margulies and George Clooney who did so, as they both attended the 51st Chaplin Award Gala in New York City on Monday, April 27, during which the latter was honored.
They had previously reunited just a year prior at the opening night of the Ocean's 11 actor's Broadway hit Good Night, and Good Luck, where they were also joined by their fellow E.R. alum and The Pitt star Noah Wyle.
E.R. was created by Michael Crichton and premiered in 1994, and though it certainly had lots of comings and goings with its cast until its finale in 2009, there's a core cast that started it. Check out these these-and-now photos of the season one cast below.
1/6
© Getty ImagesGeorge Clooney
George starred as Dr. Doug Ross, and was on the show for five seasons. He has, of course, become one of Hollywood's most beloved and bankable stars, most recently earning a Golden Globe nomination for playing the titular role in Noah Baumbach's Jay Kelly.
Since 2014, he has been married to human rights lawyer Amal Clooney (née Alamuddin), with whom he shares twins Ella and Alexander, born in 2017.
2/6
© Getty ImagesNoah Wyle
Noah played John Carter for 11 seasons, and has since returned to the (on-screen) medical field 30 years later, starring as Dr. Michael "Robby" Robinavitch in the HBO mega-hit The Pitt, which follows doctors in a Pittsburgh emergency room on their 15-hour shifts, and has already been renewed for a third season.
He has been married to wife Sara Wyle, who appeared on The Pitt season two, since 2014, and the couple are parents to daughter Frances, born in 2015, as well as Noah's kids Owen and Auden, who he shares with ex-wife Tracy Warbin.
3/6
© Getty ImagesJulianna Margulies
Julianna starred as Carol Hathaway for six seasons, winning an Emmy within the first. She is also best known for her role in another hit show, The Good Wife, in which she starred as Alicia Florrick, and which ran from 2009 to 2016.
She has been married to Keith Lieberthal, a lawyer, since 2007, and they are parents to son Kieran, born in 2008.
4/6
© Getty ImagesEriq La Salle
Eriq starred as Dr. Peter Benton for eight seasons, and went on to make guest appearances on shows such as A Gifted Man, 24, How to Make It in America, and most recently, in On Call, which aired for one season in 2025.
5/6
© Getty ImagesAnthony Edwards
Anthony starred as Mark Green, also for eight seasons, and has since made appearances on Zero Hour, Girls, Blue Bloods, Designated Survivor, Inventing Anna, and most recently WeCrashed, in 2022.
He was previously married to make-up artist Jeanine Lobell, from 1994 to 2015, with whom he shares three children, and in 2021, he eloped with Mare Winningham, who previously also worked on E.R.
6/6
© Getty ImagesSherry Stringfield
Sherry starred as Susan Lewis for the first three seasons, later returning for seasons eight through 12. She has appeared in a string of TV movies since, as well as in an episode of CSI: Crime Scene Investigation and Under the Dome, her last credit dating back to a decade ago, when she appeared in four episodes of Criminal Minds: Beyond Borders.
She is a mom two two kids, Phoebe and Milo, who she shares with ex-husband Larry Joseph.
